Secure Database Encryption using Transparent Data Encryption(TDE)

I have planned to secure the data by encrypting the entire database using Transparent Data Encryption(TDE).

I have done the same encryption in MSSQL server with .NET its works fine.

But am not sure, is that possible with Drupal and its impact. Can anyone suggest me?

Drupal version: 


Source: https://www.drupal.org/taxonomy/term/22/feed